For many patients, medications like Ozempic have transformed their weight loss journey. However, with rapid weight loss often comes an unintended consequence: Ozempic face. This term refers to the facial changes that occur after significant weight loss—like sagging skin, volume loss, and a gaunt appearance—that can leave even the healthiest patients looking tired, older, or hollow.
The good news? You don’t have to choose between a healthier body and a youthful appearance. With today’s advanced treatments, it’s possible to lift, plump, tighten, and rejuvenate your facial features, restoring balance, softness, and that signature glow.
“Ozempic face” isn’t a clinical diagnosis—it’s a nickname used to describe the cosmetic side effects of rapid weight loss in the face. When your body sheds pounds quickly, it burns both fat and volume-stabilizing elements like collagen and elastin. In the face, this loss of facial fat—especially in the cheeks, temples, and under the eyes—can cause:
These facial changes are particularly common among older patients or those with naturally thinner faces. While weight management is essential for long-term health, rapidly losing volume in your face isn’t always the goal.
Unlike more gradual weight loss, rapid weight reduction triggered by medications like Ozempic or Wegovy can leave little time for your skin to adapt. As the facial fat pads diminish, the skin may not have enough collagen or elastin to "snap back." The result? Loose skin, loss of contour, and visible signs of facial aging—even if the rest of your body feels healthier than ever.
Age also plays a role. As we get older, our skin naturally produces less collagen and elastin, making it harder to maintain firm, supple skin after significant weight loss.
Luckily, there are both non-surgical and surgical treatments that can help restore facial volume, lift sagging skin, and rejuvenate your overall facial appearance. At BEAUTY by BUFORD in Denver, CO, we specialize in customized facial rejuvenation solutions that work with your facial structure, not against it.
Here’s how we treat Ozempic face for a smoother, more youthful look.
Hyaluronic acid-based fillers like Restylane® and Juvéderm® are an excellent first step for patients dealing with mild to moderate facial volume loss. These fillers are injected into hollow areas to plump the skin, reduce fine lines, and rebuild facial contours. Common injection sites include the cheeks, nasolabial folds, marionette lines, and temples.
Fillers offer:
Sculptra isn’t your typical filler—it’s a biostimulatory injectable that works gradually to replenish lost volume by stimulating your skin’s natural collagen production. Rather than filling wrinkles or hollows directly, Sculptra encourages your body to rebuild its own structure over time, leading to smoother skin and improved facial contours that look completely natural.
Sculptra is ideal for:
With minimal downtime and effects that can last up to two years, Sculptra is a popular option for those seeking gradual, graceful rejuvenation—especially when combined with other treatments like fat transfer or RF microneedling.
If you’re looking for a more natural and longer-lasting solution, autologous fat transfer may be your ideal option. This procedure involves harvesting fat from one area of your body (like the abdomen or thighs), purifying it, and re-injecting it into the face to restore lost volume. Because the fat comes from your own body, it integrates seamlessly into the tissue and can provide permanent or semi-permanent improvement.
Fat transfer helps:
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) use your own blood’s healing properties to stimulate collagen production, tighten skin, and improve texture. These are ideal for treating fine lines, crepey skin, and enhancing the results of filler or fat grafting.
Arriessence is a next-generation biologic treatment derived from lab-grown placental stem cells. It delivers powerful regenerative proteins to the skin, stimulating collagen and elastin production from deep within. Used on its own or alongside procedures like fat grafting or microneedling, Arriessence helps:
ACORN is an innovative serum made from your own extracted follicular tissue, rich in growth factors and regenerative compounds. Often used as a topical or injectable adjunct, ACORN enhances skin texture, firmness, and tone by encouraging your body to restore and regenerate its own collagen. It's especially effective when paired with fat transfer or RF microneedling for a comprehensive boost to skin quality.
When facial drooping or lax skin is a concern, lifting procedures can help tighten sagging areas and support deeper facial tissues.
Vivace Ultra™ is an advanced RF microneedling treatment that combines precision-controlled microneedling with customizable radiofrequency energy to target the deep layers of the skin. What sets Vivace Ultra apart is its real-time imaging technology, allowing Dr. Buford to tailor the depth and intensity of treatment to your unique skin needs in real time.
By creating microchannels in the skin and delivering heat precisely where it counts, Vivace Ultra™ stimulates collagen and elastin production, improving skin texture, tightening lax skin, and softening fine lines and wrinkles. It’s especially effective for patients experiencing early facial sagging or mild skin laxity, and works beautifully in combination with fat transfer to enhance volume while refining the skin’s surface.
Renuvion combines helium plasma with radiofrequency energy to contract the skin from beneath the surface—without large incisions. This minimally invasive treatment is especially effective for patients with moderate skin laxity and can enhance the results of fat grafting by creating a firmer, more defined contour. It’s often used on the lower face, neck, or body for patients looking for skin tightening without surgery.
For patients with more advanced skin laxity, a surgical facelift or necklift may be the most effective solution. Modern facelift techniques restore facial structure by repositioning deeper tissues (not just pulling the skin tight) for natural-looking and long-lasting results.
At BEAUTY by BUFORD, board-certified plastic surgeon Dr. Gregory A. Buford is nationally recognized for his expertise in facial rejuvenation, fat grafting, and minimally invasive treatments that deliver natural-looking results.
We don’t believe in a “one-size-fits-all” fix. Every face—and every weight loss journey—is unique. That’s why Dr. Buford designs a personalized plan for each patient, combining surgical and non-surgical options based on your specific goals, facial anatomy, and overall health.
Most non-surgical treatments come with little to no downtime—usually just mild swelling or bruising that resolves in a few days. Fat grafting procedures may require 1–2 weeks of recovery, depending on how much fat was transferred and whether body sculpting was also performed. Surgical options like facelifts involve a more in-depth recovery process but deliver more dramatic and long-lasting results. No matter the treatment, Dr. Buford and his team offer a structured recovery plan that supports your healing at every stage.
You can expect personalized aftercare instructions tailored to your procedure, follow-up appointments to monitor your healing progress, and nutritional support to aid in collagen production and skin regeneration. You may also have a lymphatic massage or MEND done.
For patients undergoing fat transfer or surgical body contouring, lymphatic massage can play a key role in speeding up recovery. This gentle technique promotes drainage of excess fluid, reduces swelling, and supports circulation in treated areas. It’s especially useful for reducing puffiness and enhancing the smoothness of your final results.
MEND (Medical Nutrition Therapy) is an advanced, physician-recommended supplement protocol designed to help patients heal faster and more effectively—especially after major weight loss. Many post-weight loss patients experience muscle loss due to insufficient protein intake or rapid fat reduction. MEND helps combat that by supporting lean muscle repair, immune health, and collagen regeneration.
Dr. Buford often recommends MEND to:
Used in combination with your procedure-specific recovery plan, MEND can improve your outcome, especially when volume loss is paired with overall tissue weakness.
Losing weight can be one of the most empowering decisions you ever make. But you shouldn’t have to sacrifice your facial features or youthful appearance in the process. Whether you’re just beginning to notice signs of facial drooping or are looking to reverse more significant facial changes after weight loss, there’s a solution that’s right for you.
Dr. Buford and the BEAUTY by BUFORD team are ready to help you restore facial fullness, lift sagging skin, and rejuvenate your natural beauty. Call us today at 720-924-9649 or fill out our online form to schedule your Ozempic face fix consultation in Denver, CO.
With decades of experience, Dr. Buford has honed his skills to deliver exceptional results. Whether you're seeking to refine or rejuvenate your naturally beautiful appearance, Dr. Buford's personalized approach ensures that your needs are met with world-class skill and precision. Schedule a consultation today to put Dr. Buford’s expertise to work for you.
